Tumour Antigens Blog Post

[…] Our offering includes antibodies targeting tumour-specific antigens (e.g., oncoviral antigens and neoantigens), tumour-associated antigens (e.g., cancer germline antigens), as well as tumour markers, including those for tumour characterisation and supporting diagnosis. References […]

Anti-PLAP [H17E2] Product

Monoclonal antibody detects PLAP protein, used as a marker for various cancers, including ovarian and testicular.

Anti-CEA [161 (NCRC16)] Product

Carcinoembryonic antigen is a diagnostic marker for many cancers including colorectal, hepatoma, neuroendocrine, lung, neuroblastoma, breast, pancreatic, trophoblastic and ovarian cancers.

Summary of the IgG subclasses of five m5T4 specific monoclonal antibodies (mAb; made in 5T4KO mice) recognizing distinct epitopes in the proximal and distal 5T4 extracellular LRR containing domains (Southgate et al. 2010. PLoS One. 5(4)

Anti-5T4 [B1C3] Product

[…] expressed by trophoblast and a few specialized adult epithelia. Up-regulation of 5T4 expression in some cancers is associated with poor clinical outcome; overexpression of human 5T4 cDNA in epithelial cells […]

Summary of the IgG subclasses of five m5T4 specific monoclonal antibodies (mAb; made in 5T4KO mice) recognizing distinct epitopes in the proximal and distal 5T4 extracellular LRR containing domains (Southgate et al. 2010. PLoS One. 5(4)

Anti-5T4 [B5C9] Product

[…] expressed by trophoblast and a few specialized adult epithelia. Up-regulation of 5T4 expression in some cancers is associated with poor clinical outcome; overexpression of human 5T4 cDNA in epithelial cells […]

Summary of the IgG subclasses of five m5T4 specific monoclonal antibodies (mAb; made in 5T4KO mice) recognizing distinct epitopes in the proximal and distal 5T4 extracellular LRR containing domains (Southgate et al. 2010. PLoS One. 5(4)

Anti-5T4 [B5C12] Product

[…] expressed by trophoblast and a few specialized adult epithelia. Up-regulation of 5T4 expression in some cancers is associated with poor clinical outcome; overexpression of human 5T4 cDNA in epithelial cells […]

Summary of the IgG subclasses of five m5T4 specific monoclonal antibodies (mAb; made in 5T4KO mice) recognizing distinct epitopes in the proximal and distal 5T4 extracellular LRR containing domains. (Southgate et al. 2010. PLoS One. 5(4)

Anti-5T4 [B3F1] Product

[…] is an antagonist of the Wnt/ ?-catenin signalling pathway. Up-regulation of 5T4 expression in some cancers is associated with poor clinical outcome; overexpression of human 5T4 cDNA in epithelial cells […]

Monoclonal anti- BORIS C-terminal antibody from clone 20B11 specifically recognises the C terminal domain of BORIS; and the endogenous and exogenous BORIS protein. Cell lysates were resolved by SDS-PAGE; blotted and probed with the original mouse supernatant of the 20B11 clone. Positions of BORIS and the C-terminal domain of BORIS are indicated. B; bacterially expressed BORIS; *; 293T cells transfected with 0.5?g of the plasmid expressing BORIS; M; Molecular marker.

Anti-BORIS [20B11] mAb Product

Reagent for research, diagnostic tool. BORIS protein has been identified as Cancer-Testis Antigen (CTA) with testis-specific paralogue of the CCCTC-binding factor. Recent studies have demonstrated that d BORIS is directly […]

PASD1 Schematic exon structure of the PASD1 gene and the regions used to generate immunogens for the production of PASD1 monoclonal antibodies.

Anti-PASD1 [2ALCC128] Product

Cancer testis antigens (CTAs) such as PASD1 represent attractive immunotherapy targets, having normal tissue expression that is testis restricted and commonly widespread expression in tumours. PASD1 was originally identified […]

PASD1 Schematic exon structure of the PASD1 gene and the regions used to generate immunogens for the production of PASD1 monoclonal antibodies.

Anti-PASD1 [2ALCC136] Product

Cancer testis antigens (CTAs) such as PASD1 represent attractive immunotherapy targets, having normal tissue expression that is testis restricted and commonly widespread expression in tumours. PASD1 was originally identified […]