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Contributor Information

  • Name Julian Gannon
  • Institute Cancer Research UK, London Research Institute: Clare Hall Laboratories

Tool Details

  • Tool name: Anti-Mos [R38.1]
  • Clone: R38.1
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Xenopus laevis
  • Host: Mouse
  • Molecular weight of the target:
  • Application: ELISA ; WB
  • Strain:
  • Description: MOS (or CSF) is a mitogen-activated protein kinase kinase kinase (MAP3K) that is present in eggs during meiosis. It is destroyed after exit from meiosis II before fertilisation. It provides a good marker for studies of oocytes during oogenesis and maturation.
  • Immunogen: MBP-mos fusion protein.
  • Isotype: IgG2b
  • Research area: Cancer ; Cell Type or Organelle Marker ; Cell Signaling & Signal Transduction ; Developmental Biology ; Epigenetics & Nuclear Signalling ; Stem Cell Biology
  • Myeloma used: Sp2/0-Ag14

  • For Research Use Only

Target Details

  • Target: Mos
  • Target molecular weight:
  • Target background: MOS (or CSF) is a mitogen-activated protein kinase kinase kinase (MAP3K) that is present in eggs during meiosis. It is destroyed after exit from meiosis II before fertilisation. It provides a good marker for studies of oocytes during oogenesis and maturation.

Application Details

  • Application: ELISA ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

  • Available on request

References

  •   Nebreda et al. 1995. EMBO J. 14(22):5597-607. PMID: 8521817.
  •   Newly synthesized protein(s) must associate with p34cdc2 to activate MAP kinase and MPF during progesterone-induced maturation of Xenopus oocytes.