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Contributor Information

  • Name Nancy Hogg
  • Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details

  • Tool name: Anti-Thrombospondin receptor [SMT]
  • Alternate names: SMO
  • Clone: SMT
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: FACS ; IHC ; IP ; Fn ; WB
  • Strain: Balb/c
  • Description: CD36 is a class B scavenger receptor found in vascular endothelium, platelets and monocytes. CD36 binds thrombospondin and oxidised low density lipoprotein (LDL).
  • Immunogen: Tonsil cells and PBM
  • Isotype: IgM
  • Research area: Adhesion; Cancer; Cell Type or Organelle Marker; Cell Signaling & Signal Transduction; Metabolism; Neurobiology; Stem Cell Biology
  • Myeloma used: P3/NS1/1-Ag4.1

  • For Research Use Only

Target Details

  • Target: Thrombospondin receptor (CD36)
  • Target background: CD36 is a class B scavenger receptor found in vascular endothelium, platelets and monocytes. CD36 binds thrombospondin and oxidised low density lipoprotein (LDL).

Application Details

  • Application: FACS ; IHC ; IP ; Fn ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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  • Available on request

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References

  • •  Pilling et al. 2009. PLoS One. 4(10):e7475. PMID: 19834619.
  • •  Identification of markers that distinguish monocyte-derived fibrocytes from monocytes, macrophages, and fibroblasts.
  • •  Biswas et al. 2007. PLoS Pathog. 3(9):1271-80. PMID: 17907801.
  • •  Plasmodium falciparum uses gC1qR/HABP1/p32 as a receptor to bind to vascular endothelium and for platelet-mediated clumping.
  • •  Pain et al. 2001. Proc Natl Acad Sci U S A. 98(4):1805-10. PMID: 11172032.
  • •  Platelet-mediated clumping of Plasmodium falciparum-infected erythrocytes is a common adhesive phenotype and is associated with severe malaria.
  • •  Wintergerst et al. 2000. Eur J Biochem. 267(19):6050-9. PMID: 10998066.
  • •  Apoptosis induced by oxidized low density lipoprotein in human monocyte-derived macrophages involves CD36 and activation of caspase-3.
  • •  Hogg et al. 1984. Immunology. 53(4):753-67. PMID: 6389324.
  • •  Monoclonal antibodies specific for human monocytes, granulocytes and endothelium.