Product Image

Contributor Information

Tool Details

  • Tool name: Anti-HuR [4C8] (ChIP Grade)
  • Alternate names: ELAV-like protein 1, Human antigen R
  • Clone: 4C8
  • Tool type: Antibodies
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: ChIP ; ELISA ; IHC ; EMSA
  • Description: ELAV-like protein 1 or HuR (human antigen R) is a protein that in humans is encoded by the ELAVL1 gene. The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It stabilizes mRNAs and thereby regulates gene expression. A popular technique is to use anti-HuR antibodies to pull out interacting mRNAs and thereby analyse gene expression in a particular tissue. Monoclonal antibody 4C8 was selected by its ability to bind to the HuR/mRNA complex and thus is very useful for EMSA, ChIP and CLIP studies.
  • Immunogen: HuR peptide
  • Isotype: IgG1
  • Research area: Gene Expression

  • For Research Use Only

Target Details

  • Target: HuR
  • Target background: ELAV-like protein 1 or HuR (human antigen R) is a protein that in humans is encoded by the ELAVL1 gene. The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It stabilizes mRNAs and thereby regulates gene expression. A popular technique is to use anti-HuR antibodies to pull out interacting mRNAs and thereby analyse gene expression in a particular tissue. Monoclonal antibody 4C8 was selected by its ability to bind to the HuR/mRNA complex and thus is very useful for EMSA, ChIP and CLIP studies.

Application Details

  • Application: ChIP ; ELISA ; IHC ; EMSA

Handling

  • Format: Liquid
  • Storage buffer:
  • Storage conditions:
  • Shipping conditions: Shipping at 4°C

Documentation

  • Available on request