ANTIBODIES
Contributor Information
- Institute Netherlands Cancer Institute
Tool Details
- Tool name: Anti-CD44 [NKI-P1]
- Alternate names: Hematopoietic Cell E- And L-Selectin Ligand; Heparan Sulfate Proteoglycan; Hermes Antigen
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Molecular weight of the target: 84 kDa
- Application: FACS ; IHC ; IP
- Strain: Balb/c
- Description: CD44 antigen is a cell-surface glycoprotein involved in cellâÂÂcell interactions, cell adhesion and migration. CD44 is expressed in a large number of mammalian cell types and participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, haematopoiesis, and tumour metastasis.
- Immunogen: A mouse was immunized rasplenically with immunoprecipitated LFA-I family antigen. The immunoprecipitates were obtained from lysates of human monocytes by centrifugal elutriation (>90% pure).
- Isotype: IgG1
- Research area: Adhesion; Cell Structure and Motility; Immunology
- Myeloma used: Sp2/0-Ag14
- For Research Use Only
Target Details
- Target: CD44
- Target molecular weight: 84 kDa
- Target background: CD44 antigen is a cell-surface glycoprotein involved in cellcell interactions, cell adhesion and migration. CD44 is expressed in a large number of mammalian cell types and participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, haematopoiesis, and tumour metastasis.
Application Details
- Application: FACS ; IHC ; IP
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15°C to -25°C
- Shipping conditions: Shipping at 4°C
Documentation
- Available on request
References
- • Pals et al. 1989. J Immunol. 143(3):851-7. PMID: 2663988.
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