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Contributor Information

  • Institute Absolute Antibody ; University of Oxford

Tool Details

  • Tool name: Anti-FCGR3 [DJ130c]
  • Clone: DJ130c
  • Tool type: Antibodies
  • Class: Recombinant
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Description: FCGR3 mediates phagocytosis and antibody-dependent cell-mediated cytotoxicity. It is expressed on neutorphils, NK cells and macrophages
  • Immunogen: CD16
  • Isotype: IgG1
  • Research area: Cell Type or Organelle Marker ; Immunology ; Stem Cell Biology

  • For Research Use Only

Target Details

  • Target: Fc gamma receptor III (FCGR3, CD16, Leu II)
  • Target background: FCGR3 mediates phagocytosis and antibody-dependent cell-mediated cytotoxicity. It is expressed on neutorphils, NK cells and macrophages

Application Details

Handling

  • Format: Liquid
  • Storage buffer:
  • Storage conditions:
  • Shipping conditions: Shipping at 4°C

Documentation

  • Available on request

References

  •   HĂśnig et al. 1999. J Leukoc Biol. 66(3):429-36. PMID: 10496313.
  •   Intracellular expression of Fc gamma RIII (CD16) and its mobilization by chemoattractants in human eosinophils.
  •   Schmidt RE (1993) CD16 cluster workshop report. In Schlossman SF, et al (eds) Leucocyte Typing V, Vol 1, Oxford University Press, Oxford, New York and Tokyo, p 805-806
  •   Synovial PMN show a coordinated up-regulation of CD66 molecules.
  •   Zhu et al. 1998. J Immunol. 161(5):2574-9. PMID: 9725258.