ANTIBODIES

Contributor Information
- Name Nancy Hogg
- Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
- Tool name: Anti-HLAD/DR, DQ [35]
- Clone: 35
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Molecular weight of the target:
- Application: FACS ; IHC ; IP
- Description: Human Leukocyte Antigens (HLA) are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). Clone 35 can be used for HLA typing, cytotoxic, binding and biochemical assays.
- Immunogen:
- Isotype: IgG3
- Research area: Immunology
- For Research Use Only
Target Details
- Target: Human Leukocyte Antigen (HLA) D/DR, DQ (MHC Class II)
- Target molecular weight:
- Target background: Human Leukocyte Antigens (HLA) are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). Clone 35 can be used for HLA typing, cytotoxic, binding and biochemical assays.
Application Details
- Application: FACS ; IHC ; IP
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15°C to -25°C
- Shipping conditions: Shipping at 4°C
Related Tools
References
- • Allen et al. 1987. Cancer Res. 47(11):2919-23. PMID: 3105871.
- • Association of colorectal tumor epithelium expressing HLA-D/DR with CD8-positive T-cells and mononuclear phagocytes.