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Contributor Information

  • Name Nancy Hogg
  • Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details

  • Tool name: Anti-HLAD/DR, DQ [35]
  • Clone: 35
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Molecular weight of the target:
  • Application: FACS ; IHC ; IP
  • Description: Human Leukocyte Antigens (HLA) are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). Clone 35 can be used for HLA typing, cytotoxic, binding and biochemical assays.
  • Immunogen:
  • Isotype: IgG3
  • Research area: Immunology

  • For Research Use Only

Target Details

  • Target: Human Leukocyte Antigen (HLA) D/DR, DQ (MHC Class II)
  • Target molecular weight:
  • Target background: Human Leukocyte Antigens (HLA) are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). Clone 35 can be used for HLA typing, cytotoxic, binding and biochemical assays.

Application Details

  • Application: FACS ; IHC ; IP

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

  • Available on request

References

  •   Allen et al. 1987. Cancer Res. 47(11):2919-23. PMID: 3105871.
  •   Association of colorectal tumor epithelium expressing HLA-D/DR with CD8-positive T-cells and mononuclear phagocytes.