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Contributor Information

  • Name Sharon Tooze
  • Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details

  • Tool name: Anti-SGII [SGII 6B1/3]
  • Clone: SGII 6B1/3
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Rat
  • Host: Mouse
  • Application: IF ; ICC ; FACS ; IHC ; IF ; IP ; WB
  • Description: SGII6B1/3 has potential uses for chromatogranin diagnostics.
  • Immunogen: Peptide from rat SGII (C terminus of p18: KEENSRENPF)
  • Isotype: IgG2b
  • Research area: Neurobiology
  • Myeloma used: Sp2/0-Ag14

  • For Research Use Only

Target Details

  • Target: Secretogranin (SG II)
  • Target background: SgII is a member of the chromogranin family of secretory proteins. SgII is stored in neuroendocrine cells involved in hormone packaging.

Application Details

  • Application: IF ; ICC ; FACS ; IHC ; IF ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -20°C
  • Shipping conditions: Shipping at 4°C

Documentation

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  • Available on request

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References

  • •  akmakli et al. 2018. Noro Psikiyatr Ars. 55(1):73-79. PMID: 30042645.
  • •  Berard et al. 2015. J Virol. 89(23):11954-64. PMID: 26378181.
  • •  Chen et al. 2015. Biophys Rep. 1:34-40. PMID: 26942217.
  • •  Oh et al. 2012. EMBO Mol Med. 4(5):435-48. PMID: 22359280.
  • •  Identification of the HSPB4/TLR2/NF-B axis in macrophage as a therapeutic target for sterile inflammation of the cornea.
  • •  Urb et al. 1998. J Cell Biol. 143(7):1831-44. PMID: 9864358.
  • •  Homotypic fusion of immature secretory granules during maturation in a cell-free assay.
  • •  Ditti et al. 1995. Biochem J. 310 ( Pt 3):777-87. PMID: 7575410.
  • •  Characterization of the endopeptidase PC2 activity towards secretogranin II in stably transfected PC12 cells.