ANTIBODIES
Contributor Information
- Name Helen Hurst
- Institute Queen Mary Innovation Ltd
Tool Details
- Tool name: Anti-AP2b [AP2b? 1F3/8]
- Clone: AP2b? 1F3/8
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Molecular weight of the target: 50 kDa
- Application: ELISA ; IHC ; WB
- Strain: Balb/c
- Description: AP-2 is a family of developmentally regulated transcription factors which also play a role in breast cancer and melanoma. AP-2? may be important in cardiac and kidney development. The AP-2 transcription factors form the OB2 complex that has been shown to up-regulate c-erb-B2 transcription.
- Immunogen: Truncated AP-2? protein prepared from bacteria
- Isotype: IgG2a
- Research area: Cancer; Epigenetics & Nuclear Signalling
- Myeloma used: Sp2/0-Ag14
- For Research Use Only
Target Details
- Target: Activating Protein 2 (AP-2) beta
- Target molecular weight: 50 kDa
- Target background: AP-2 is a family of developmentally regulated transcription factors which also play a role in breast cancer and melanoma. AP-2? may be important in cardiac and kidney development. The AP-2 transcription factors form the OB2 complex that has been shown to up-regulate c-erb-B2 transcription.
Application Details
- Application: ELISA ; IHC ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15°C to -25°C
- Shipping conditions: Shipping at 4°C
Documentation
- Available on request
References
- • Ebauer et al. 2007. Oncogene. 26(51):7267-81. PMID: 17525748.
- • Comparative expression profiling identifies an in vivo target gene signature with TFAP2B as a mediator of the survival function of PAX3/FKHR.
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