ANTIBODIES
Contributor Information
- Name Stephen West
- Institute Cancer Research UK, London Research Institute: Clare Hall Laboratories
Tool Details
- Tool name: Anti-Rad51B [Rad51B 1E11/6]
- Clone: Rad51B 1E11/6
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human ; Hamster
- Host: Mouse
- Molecular weight of the target:
- Application: WB
- Strain: Balb/c
- Description: RAD51B is a Rad51 paralog. RAD51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologous recombination DNA repair pathway. RAD51 forms a nucleoprotein filament (through binding RAD52 and single stranded DNA that are exposed following double strand breaks) that initiates recombination. RAD51B is also a component for the homologous recombination pathway.
- Immunogen: Raised against His-tagged human Rad51B, overexpressed in e.coli and purified on a talon affinity column under denaturing conditions, followed by gel purification using SDS-PAGE.
- Isotype: IgG1
- Research area: Genetics
- Myeloma used: Sp2/0-Ag14
- For Research Use Only
Target Details
- Target: Rad51B
- Target molecular weight:
- Target background: RAD51B is a Rad51 paralog. RAD51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologous recombination DNA repair pathway. RAD51 forms a nucleoprotein filament (through binding RAD52 and single stranded DNA that are exposed following double strand breaks) that initiates recombination. RAD51B is also a component for the homologous recombination pathway.
Application Details
- Application: WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15Ă°C to -25Ă°C
- Shipping conditions: Shipping at 4Ă°C
Documentation
Related Tools
References
- • French et al. 2002. J Biol Chem. 277(22):19322-30. PMID: 11912211.
- • Role of mammalian RAD51L2 (RAD51C) in recombination and genetic stability.
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