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Contributor Information

  • Institute University of Leeds

Tool Details

  • Tool name: Anti-EB1 [EB1-CL 1A11/4]
  • Clone: EB1-CL 1A11/4
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human ; Primate ; Dog
  • Host: Mouse
  • Molecular weight of the target:
  • Application: ELISA ; IF ; IHC ; IP ; WB
  • Strain: CD1
  • Description: EB1 is a microtubule tip-associated protein that interacts with the APC tumour suppressor protein and components of the dynein/dynactin complex.
  • Immunogen: EB1 deltaC1 mutant
  • Isotype: IgG2b
  • Research area: Cancer; Cell Type or Organelle Marker; Cell Signaling & Signal Transduction
  • Myeloma used: Sp2/0-Ag14

  • For Research Use Only

Target Details

  • Target: EB1
  • Target molecular weight:
  • Target background: EB1 is a microtubule tip-associated protein that interacts with the APC tumour suppressor protein and components of the dynein/dynactin complex.

Application Details

  • Application: ELISA ; IF ; IHC ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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  • Available on request

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References

  • •  Bowen et al. 2011. J Cell Biol. 194(2):187-97. PMID: 21788367.
  • •  Septin GTPases spatially guide microtubule organization and plus end dynamics in polarizing epithelia.
  • •  Askham et al. 2002. Mol Biol Cell. 13(10):3627-45. PMID: 12388762.
  • •  Evidence that an interaction between EB1 and p150(Glued) is required for the formation and maintenance of a radial microtubule array anchored at the centrosome.