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Contributor Information

  • Name Karen Pulford
  • Institute University of Oxford

Tool Details

  • Tool name: Anti-TAL1 [BTL73]
  • Clone: BTL73
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: ChIP ; ELISA ; IHC ; WB
  • Description: Monoclonal antibody which stains 3 forms of TAL1 in the cytoplasm and nuclei of cells.
  • Immunogen: TAL-1 recombinant protein
  • Immunogen UniProt ID: P17542
  • Isotype: IgG1
  • Research area: Cancer ; Cell Cycle ; Developmental Biology ; Epigenetics & Nuclear Signalling ; Stem Cell Biology
  • Myeloma used: P3/NS1/1-Ag4.1

  • For Research Use Only

Target Details

  • Target: TAL1
  • Target background: Monoclonal antibody which stains 3 forms of TAL1 in the cytoplasm and nuclei of cells.

Application Details

  • Application: ChIP ; ELISA ; IHC ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: Store at -20°C frozen. Avoid repeated freeze / thaw cycles
  • Shipping conditions: Shipping at 4°C

Documentation

  • Available on request

References

  •   Christophersen et al. 2017. Sci Rep. 7:40451. PMID: 28084402.
  •   Farrell et al. 2011. Blood. 117(18):4935-45. PMID: 21385855.
  •   A 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expression.
  •   Goardon et al. 2002. Blood. 100(2):491-500. PMID: 12091340.
  •   Ectopic expression of TAL-1 protein in Ly-6E.1-htal-1 transgenic mice induces defects in B- and T-lymphoid differentiation.
  •   Delabesse et al. 1998. Br J Haematol. 102(2):449-57. PMID: 9695959.
  •   TAL1 expression does not occur in the majority of T-ALL blasts.
  •   Bernard et al. 1995. Blood. 85(11):3356-7. PMID: 7756670.
  •   Nuclear localization of the SCL/TAL1 basic helix-loop-helix protein is not dependent on the presence of the basic domain.
  •   Pulford et al. 1995. Blood. 85(3):675-84. PMID: 7833471.
  •   Expression of TAL-1 proteins in human tissues.