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Contributor Information

  • Name Margaret Goodall ; D.L. Hardie ; Roy Jefferis ; Ian MacLennen
  • Institute University of Birmingham

Tool Details

  • Tool name: Anti-CD72 [BU40]
  • Alternate names: CD72 Molecule; CD72 Antigen; Lyb-2; CD72b; LYB2
  • Clone: BU40
  • Tool type: Antibodies
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: FACS ; IHC; IP ; WB
  • Description: CD72, a member of the C-type lectin superfamily, is a 45 kDa type II transmembrane glycoprotein. It is expressed from the pro-B through to the mature B cell stage but absent in terminally differntiated plasma cells. Ligation of CD72 enhances B cell growth and proliferation.
  • Immunogen: HF B1 plasmacytoid cell line. Considered to be “late B like”.
  • Isotype: IgG2a kappa
  • Research area: Immunology ; Stem Cell Biology

  • For Research Use Only

Target Details

  • Target: CD72
  • Target background: CD72, a member of the C-type lectin superfamily, is a 45 kDa type II transmembrane glycoprotein. It is expressed from the pro-B through to the mature B cell stage but absent in terminally differntiated plasma cells. Ligation of CD72 enhances B cell growth and proliferation.

Application Details

  • Application: FACS ; IHC; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: RPMI 1640 + 10% FCS
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

  • Available on request

References

  •   Ishida I. et al. 2003. International Immunology. 15(8):1027-34. PMID: 12882840 Knapp W. et al. 1989. Leukocyte Typing IV. Oxford University Press. ISBN-13: 978-0192618672 Schwarting R. et al. 1992. Am.J. of Hematol. 41(3):151-8. PMID: 1384316 Van De Velde H. et al. 1991. Nature 351(6328):662-5. PMID: 1711157