ANTIBODIES
Contributor Information
- Name Margaret Goodall ; D.L. Hardie ; Roy Jefferis ; Ian MacLennen
- Institute University of Birmingham
Tool Details
- Tool name: Anti-CD72 [BU40]
- Alternate names: CD72 Molecule; CD72 Antigen; Lyb-2; CD72b; LYB2
- Clone: BU40
- Tool type: Antibodies
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: FACS ; IHC; IP ; WB
- Description: CD72, a member of the C-type lectin superfamily, is a 45 kDa type II transmembrane glycoprotein. It is expressed from the pro-B through to the mature B cell stage but absent in terminally differntiated plasma cells. Ligation of CD72 enhances B cell growth and proliferation.
- Immunogen: HF B1 plasmacytoid cell line. Considered to be late B like.
- Isotype: IgG2a kappa
- Research area: Immunology ; Stem Cell Biology
- For Research Use Only
Target Details
- Target: CD72
- Target background: CD72, a member of the C-type lectin superfamily, is a 45 kDa type II transmembrane glycoprotein. It is expressed from the pro-B through to the mature B cell stage but absent in terminally differntiated plasma cells. Ligation of CD72 enhances B cell growth and proliferation.
Application Details
- Application: FACS ; IHC; IP ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Storage buffer: RPMI 1640 + 10% FCS
- Storage conditions: -15°C to -25°C
- Shipping conditions: Shipping at 4°C
Documentation
- Available on request
References
- • Ishida I. et al. 2003. International Immunology. 15(8):1027-34. PMID: 12882840 Knapp W. et al. 1989. Leukocyte Typing IV. Oxford University Press. ISBN-13: 978-0192618672 Schwarting R. et al. 1992. Am.J. of Hematol. 41(3):151-8. PMID: 1384316 Van De Velde H. et al. 1991. Nature 351(6328):662-5. PMID: 1711157
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