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Contributor Information

  • Name Patrick Varga-Weisz
  • Institute Marie Curie Research Institute

Tool Details

  • Tool name: Anti-SNF2L [SNF2L]
  • Clone: SNF2L
  • Tool type: Antibodies
  • Tool sub-type: Primary Antibody
  • Class: Polyclonal
  • Purpose: Marker
  • Conjugate: Unconjugated
  • Reactivity: Human ; Mouse
  • Host: Rabbit
  • Molecular weight of the target: 122 kDa
  • Application: WB
  • Immunogen: Peptide coupled to keyhole limpet hemocyanin
  • Research area: Epigenetics & Nuclear Signalling

  • For Research Use Only

Target Details

  • Target: SNF2L
  • Target molecular weight: 122 kDa
  • Target background: SNF2L is a human homolog of the budding yeast Snf2 protein, and is a member of the SWI/SNF family of proteins. The members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. SNF2L is similar in sequence to the Drosophila ISWI chromatin remodelling protein. In mouse SNF2L expression is restricted to the central nervous system and gonadal tissue. Whereas in human SNF2L is expressed ubiquitously, and regulation is mediated by isoform variation.

Application Details

  • Application: WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage conditions: -80°C
  • Shipping conditions: Shipping at 4°C
  • Mycoplasma free: Yes

Documentation

  • Available on request

References

  •   Bozhenok et al. 2002. EMBO J. 21(9):2231-41. PMID: 11980720.
  •   WSTF-ISWI chromatin remodeling complex targets heterochromatic replication foci.