ANTIBODIES

Contributor Information
- Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
- Tool name: Anti-CLEC9A [7H11]
- Alternate names: C-Type Lectin Domain Family 9 Member A; HEEE9341; UNQ9341; DNGR-1; CD37; DNGR1
- Clone: 7H11
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Mouse
- Host: Rat
- Application: ELISA ; FACS ; IF ; IP ; WB
- Description: Recognises mouse DNGR-1, also known as CLEC9A, which is a highly specific marker of the CD8a+ and the CD103+ DC subsets, as well as a receptor able to recognise a preformed signal exposed on necrotic cells.
- Immunogen: RBL-2H3 cells expressing mouse DNGR-1 fused to an HA epitope
- Isotype: IgG1
- Research area: Immunology ; Stem Cell Biology
- Myeloma used: Y3.AG.1.2.3
- For Research Use Only
Target Details
- Target: Mouse DNGR1
- Target background: Recognises mouse DNGR-1, also known as CLEC9A, which is a highly specific marker of the CD8a+ and the CD103+ DC subsets, as well as a receptor able to recognise a preformed signal exposed on necrotic cells.
Application Details
- Application: ELISA ; FACS ; IF ; IP ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15°C to -25°C
- Shipping conditions: Shipping at 4°C
Related Tools
References
- • Joffre et al. 2010. Eur J Immunol. 40:1255-65. [PMID: 20333625]
- • Sancho et al. 2008. J Clin Invest 118:2098-110 .[PMID: 18497879]
- • Sancho et al. 2009. Nature. 458:899-903. [PMID: 19219027]
- • Li et al. 2015. Eur J Immunol. 45(3):854-64. PMID: 25487143.