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Contributor Information

  • Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details

  • Tool name: Anti-CLEC9A [7H11]
  • Alternate names: C-Type Lectin Domain Family 9 Member A; HEEE9341; UNQ9341; DNGR-1; CD37; DNGR1
  • Clone: 7H11
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Mouse
  • Host: Rat
  • Application: ELISA ; FACS ; IF ; IP ; WB
  • Description: Recognises mouse DNGR-1, also known as CLEC9A, which is a highly specific marker of the CD8a+ and the CD103+ DC subsets, as well as a receptor able to recognise a preformed signal exposed on necrotic cells.
  • Immunogen: RBL-2H3 cells expressing mouse DNGR-1 fused to an HA epitope
  • Isotype: IgG1
  • Research area: Immunology ; Stem Cell Biology
  • Myeloma used: Y3.AG.1.2.3

  • For Research Use Only

Target Details

  • Target: Mouse DNGR1
  • Target background: Recognises mouse DNGR-1, also known as CLEC9A, which is a highly specific marker of the CD8a+ and the CD103+ DC subsets, as well as a receptor able to recognise a preformed signal exposed on necrotic cells.

Application Details

  • Application: ELISA ; FACS ; IF ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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  • Available on request

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References

  • •  Joffre et al. 2010. Eur J Immunol. 40:1255-65. [PMID: 20333625]
  • •  Sancho et al. 2008. J Clin Invest 118:2098-110 .[PMID: 18497879]
  • •  Sancho et al. 2009. Nature. 458:899-903. [PMID: 19219027]
  • •  Li et al. 2015. Eur J Immunol. 45(3):854-64. PMID: 25487143.