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Contributor Information

  • Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details

  • Tool name: Anti-CLEC9A [8F9]
  • Clone: 8F9
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Molecular weight of the target:
  • Application: FACS ; IHC ; FACS ; IF
  • Strain: Balb/c
  • Description: Recognises human DNGR-1, also known as CLEC9A, which is a highly specific marker of a human DC subset, as well as a receptor able to recognise a preformed signal exposed on necrotic cells.
  • Immunogen: RBL-2H3 cells expressing human DNGR-1 fused to an HA epitope
  • Isotype: IgG2a
  • Research area: Immunology ; Stem Cell Biology
  • Myeloma used: Sp2/0-Ag14

  • For Research Use Only

Target Details

  • Target: Human DNGR1
  • Target molecular weight:
  • Target background: Recognises human DNGR-1, also known as CLEC9A, which is a highly specific marker of a human DC subset, as well as a receptor able to recognise a preformed signal exposed on necrotic cells.

Application Details

  • Application: FACS ; IHC ; FACS ; IF

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

  • Available on request

References

  •   Poulin et al. 2010. J Exp Med. 207:1261-71. [PMID: 20479117]
  •   Sancho et al. 2008. J Clin Invest 118:2098-110 .[PMID: 18497879]
  •   Sancho et al. 2009. Nature. 458:899-903. [PMID: 19219027]
  •   Canavan et al. 2018. JCI Insight. 3(23):. PMID: 30518680.