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Contributor Information

  • Institute University of Cambridge

Tool Details

  • Tool name: Anti-RttnN [Rttn1]
  • Clone: Rttn1
  • Tool type: Antibodies
  • Class: Polyclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Rabbit
  • Application: IF
  • Description: Involved in the genetic cascade that governs left-right specification. Required for correct asymmetric expression of NODAL, LEFTY and PITX2. This antibody recognises the N-terminal section of the the rttn protein (aa 343-584).
  • Immunogen: Maltose-binding protein (MBP) fusion proteins
  • Research area: Developmental Biology

  • For Research Use Only

Target Details

  • Target: Human RttnN Terminal
  • Target background: Involved in the genetic cascade that governs left-right specification. Required for correct asymmetric expression of NODAL, LEFTY and PITX2. This antibody recognises the N-terminal section of the the rttn protein (aa 343-584).

Application Details

  • Application: IF

Handling

  • Format: Liquid
  • Shipping conditions: Shipping at 4°C

Documentation

  • Available on request

References

  •   Stevens et al. 2009. J Cell Biol. 187(3):355-63. PMID: 19948479.
  •   Ana3 is a conserved protein required for the structural integrity of centrioles and basal bodies.