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Contributor Information

  • Name Ayham Alnabulsi
  • Institute Absolute Antibody ; Vertebrate Antibodies Limited

Tool Details

  • Tool name: Anti-TNFRSF18 (soluble form) [T10P2H9*B9]
  • Alternate names: Tumor Necrosis Factor Receptor Superfamily Member 18; Glucocorticoid-Induced TNFR-Related Protein; Activation-Inducible TNFR Family Receptor; AITR; GITR; TNF Receptor Superfamily Activation-Inducible Protein; CD357 Antigen; GITR-D; CD357
  • Clone: rT10P2H9*B9
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Recombinant
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Molecular weight of the target: 26 kDa
  • Application: ELISA ; IHC ; WB
  • Immunogen: Ovalbumin conjugated peptide - PWQQKWVQE
  • Research area: Cell Signaling & Signal Transduction

  • For Research Use Only

Target Details

  • Target: Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18-soluble form), GITR
  • Target molecular weight: 26 kDa
  • Target background: TNFRSF18 is a type I transmembrane protein with homology to members of divergent costimulatory molecules in the TNFRSF. To date three isoforms of TNFRSF18 have been identified, including one soluble form that lacks a transmembrane domain. According to homology of the cytoplasmic domain, TNFRSF18 and other three TNFRSF members (41BB, CD27, and OX40) probably constitute a new subfamily as divergent costimulators. TNFRSF18 and the other subfamily members bind TRAF molecules and activate NF-KB.

Application Details

  • Application: ELISA ; IHC ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS
  • Shipping conditions: Shipping at 4°C

Documentation

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  • Available on request

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