ANTIBODIES
Contributor Information
- Name Elena Klenova
- Institute Absolute Antibody ; University of Essex
Tool Details
- Tool name: Anti-BORIS [20B11]
- Alternate names: Brother of the regulator of imprinted sites, Cancer/testis antigen 27, CCCTC binding factor (zinc finger protein) like, CCCTC-binding factor, CT27, CTCF paralog, CTCF T, CTCF-like protein, Ctcfl, CTCFL_HUMAN, dJ579F2.2, HMG 1L1, HMGB1L1, MGC163358, MGC16915, MGC16916
- Clone: 20B11
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Recombinant
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: ChIP ; ELISA ; IHC ; IF ; IP ; WB
- Description: Reagent for research, diagnostic tool. BORIS protein has been identified as Cancer-Testis Antigen (CTA) with testis-specific paralogue of the CCCTC-binding factor. Recent studies have demonstrated that d BORIS is directly responsible for the transcriptional activation of TSP50 (testes-specific protease 50).
- Immunogen: Synthetic peptide within the BORIS C-terminal domain (aa 614-648) (CG)GEMFPVACRETTARVKEE (NB - the first two aa do not belong to BORIS)
- Isotype: IgG3 kappa
- Research area: Cancer ; Epigenetics & Nuclear Signalling
- For Research Use Only
Target Details
- Target: BORIS
- Target background: Reagent for research, diagnostic tool. BORIS protein has been identified as Cancer-Testis Antigen (CTA) with testis-specific paralogue of the CCCTC-binding factor. Recent studies have demonstrated that d BORIS is directly responsible for the transcriptional activation of TSP50 (testes-specific protease 50).
Application Details
- Application: ChIP ; ELISA ; IHC ; IF ; IP ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Storage buffer: PBS
- Shipping conditions: Shipping at 4°C
Documentation
- Available on request
References
- • Debruyne et al. 2019. Nature. 572(7771):676-680. PMID: 31391581.
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