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Contributor Information

  • Name Ayham Alnabulsi
  • Institute Absolute Antibody ; Vertebrate Antibodies Limited

Tool Details

  • Tool name: Anti-sCD40 (soluble) [T8P2G4*A6]
  • Alternate names: CD4 Molecule; CD4L Receptor; TNFRSF5; CDW4; Bp5; Tumor Necrosis Factor Receptor Superfamily; Member; B Cell Surface Antigen CD4; CD4 Antigen; P5
  • Clone: T8P2G4*A6
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Recombinant
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA ; IHC ; WB
  • Description: CD40 is a 48 kD type I glycoprotein and a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 is also expressed on a wide range of tumor cells, including non-Hodgkin's and Hodgkin's lymphomas, myeloma and some carcinomas including nasopharynx, bladder, cervix, kidney and ovary.The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects.
  • Immunogen: Ovalbumin-conjugated synthetic peptide RDPVCHPLGA (C-terminal sequence)
  • Isotype: IgG1 kappa
  • Research area: Cancer ; Immunology

  • For Research Use Only

Target Details

  • Target: CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40 soluble form)
  • Target background: CD40 is a 48 kD type I glycoprotein and a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 is also expressed on a wide range of tumor cells, including non-Hodgkin's and Hodgkin's lymphomas, myeloma and some carcinomas including nasopharynx, bladder, cervix, kidney and ovary.The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects.

Application Details

  • Application: ELISA ; IHC ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS
  • Shipping conditions: Shipping at 4°C

Documentation

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  • Available on request

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