Cat. #153324
Anti-CEACAM6 (CD66c) [1H7-4B]
Cat. #: 153324
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 1-2 weeks
Target: CEACAM6, CD66c
Class: Monoclonal
Application: ELISA ; FACS ; IHC ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Bernhard B. Singer
Institute: LeukoCom
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-CEACAM6 (CD66c) [1H7-4B]
- Alternate name: CD66c
- Clone: 1H7-4B
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 90 kDa
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; FACS ; IHC ; WB
- Description: CEACAM6 is a glycosyl phosphatidyl inositol (GPI) linked glycoprotein. CEACAM6 expression is upregulated in many adenocarcinomas and leukemias. CEACAM6 is expressed in epithelial cells of the fetal and adult gastrointestinal tract, epithelia of glandular tissues, squamous epithelial cell of the tongue, esophagus and cervix as well as on granulocytes.
- Immunogen: Recombinant human CEACAM6 extracellular domain.
- Isotype: IgG1 kappa
- Myeloma used: P3/NS1/1-Ag4.1
Target Details
- Target: CEACAM6, CD66c
- Molecular weight: 90 kDa
- Target background: CEACAM6 is a glycosyl phosphatidyl inositol (GPI) linked glycoprotein. CEACAM6 expression is upregulated in many adenocarcinomas and leukemias. CEACAM6 is expressed in epithelial cells of the fetal and adult gastrointestinal tract, epithelia of glandular tissues, squamous epithelial cell of the tongue, esophagus and cervix as well as on granulocytes.
Applications
- Application: ELISA ; FACS ; IHC ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -80° C
- Shipping conditions: Shipping at 4° C
References
- Singer et al. 2014. PLoS One. 9(4):e94106. PMID: 24743304.
- Soluble CEACAM8 interacts with CEACAM1 inhibiting TLR2-triggered immune responses.
- Muturi et al. 2013. PLoS One. 8(9):e74654. PMID: 24040308.
- Tumor and endothelial cell-derived microvesicles carry distinct CEACAMs and influence T-cell behavior.
- Klaile et al. 2013. Respir Res. 14:85. PMID: 23941132.
- Carcinoembryonic antigen (CEA)-related cell adhesion molecules are co-expressed in the human lung and their expression can be modulated in bronchial epithelial cells by non-typable Haemophilus influenzae, Moraxella catarrhalis, TLR3, and type I and II int
