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Contributor Information

  • Institute University College London (UCL) ; Absolute Antibody

Tool Details

  • Tool name: Anti-Factor VII [RFF-VII/1]
  • Clone: rRFF-VII/1
  • Tool type: Antibodies
  • Class: Recombinant
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA ; Fn ; WB
  • Description: Factor VII is a 50kDa multi-domain, single chain plasma glycoprotein synthesised in the liver. It is essential for blood coagulation. Factor VII is converted to the active, two chain, serine protease Factor VIIa via cleavage by thrombin, factor Xa, factor IXa or factor XIIa. Factor VIIa converts factor X to factor Xa, which in turn converts prothrombin to thrombin. This monoclonal antibody partially inhibits human Factor VII activity.
  • Immunogen: Purified human factor VII
  • Isotype: IgG1 kappa
  • Research area: Cardiovascular

  • For Research Use Only

Target Details

  • Target: Factor VII
  • Target background: Factor VII is a 50kDa multi-domain, single chain plasma glycoprotein synthesised in the liver. It is essential for blood coagulation. Factor VII is converted to the active, two chain, serine protease Factor VIIa via cleavage by thrombin, factor Xa, factor IXa or factor XIIa. Factor VIIa converts factor X to factor Xa, which in turn converts prothrombin to thrombin. This monoclonal antibody partially inhibits human Factor VII activity.

Application Details

  • Application: ELISA ; Fn ; WB

Handling

  • Format: Liquid
  • Concentration: 1mg/ml
  • Storage buffer: PBS
  • Shipping conditions: Shipping at 4°C

Documentation

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  • Available on request

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References

  • •  Original hybridoma first published in: Takase et al. 1988. J Clin Pathol. 41(3):337-41. PMID: 3360957.