ANTIBODIES

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Anti-IFN-Gammarel [VAB4P2B4*E8]

Cat. #153451

Tool name: Anti-IFN-Gammarel [VAB4P2B4*E8]
Alternate names: IFG antibody, IFI antibody, IFN gamma antibody, IFN immune antibody, IFN-gamma antibody, IFNG antibody, Immune interferon antibody, Interferon gamma antibody
Clone: VAB4P2B4*E8
Tool type: Antibodies
Class: Monoclonal
Conjugate: Unconjugated
Reactivity: Salmon ; Brown Trout
Host: Mouse
Molecular weight of the target: 22 kDa
Application: ELISA ; IHC ; WB
Strain: Balb/c
Description: Interferons (IFNs) were originally identified as proteins that induce an antiviral state in cells, but they also have important regulatory functions in the immune system. Type I IFN (predominantly IFN-ÄÂ? and IFN-ÄÂ?) and type II IFN (IFN-ÄÂ?) play critical roles in innate and adaptive immune response against viral infection in mammals. Unlike mammals fish have two type II interferons, IFN-ÄÂ? and IFN-ÄÂ?-related (IFN-ÄÂ?rel). IFN-ÄÂ? and IFN-ÄÂ?rel have recently been shown to play a role in protecting particular species of fish against infection by pathogens such as infectious pancreatic necrosis virus (IPNV) and salmonid alphavirus 3 (SAV3). VAB4P2B4*E8 can be used to study IFN-ÄÂ?rel in Atlantic salmon (Salmo salar) and Brown trout (Salmo trutta).
Immunogen: ovalbumin-conjugated synthetic peptide-DLKRSYYQDR; peptide immunogen is 90% identical to rainbow trout (Oncorhynchus mykiss)
Isotype: IgG
Research area: Immunology
Myeloma used: P3X63Ag8.653

Target: Anti-IFN-ÄÂ?rel
Target molecular weight: 22 kDa
Target background: Interferons (IFNs) were originally identified as proteins that induce an antiviral state in cells, but they also have important regulatory functions in the immune system. Type I IFN (predominantly IFN-ÄÂ? and IFN-ÄÂ?) and type II IFN (IFN-ÄÂ?) play critical roles in innate and adaptive immune response against viral infection in mammals. Unlike mammals fish have two type II interferons, IFN-ÄÂ? and IFN-ÄÂ?-related (IFN-ÄÂ?rel). IFN-ÄÂ? and IFN-ÄÂ?rel have recently been shown to play a role in protecting particular species of fish against infection by pathogens such as infectious pancreatic necrosis virus (IPNV) and salmonid alphavirus 3 (SAV3). VAB4P2B4*E8 can be used to study IFN-ÄÂ?rel in Atlantic salmon (Salmo salar) and Brown trout (Salmo trutta).

Application: ELISA ; IHC ; WB
Application notes: Recommended Usage Conditions: ELISA- neat, Western Blot- neat, IHC- 1/3, antigen retrieval: microwave 20 min @ 800W in 10 mM citrate buffer, pH 6.0

£ 300
This fee is applicable only for non-profit organizations

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