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Contributor Information

  • Name Ayham Alnabulsi
  • Institute Vertebrate Antibodies Limited

Tool Details

  • Tool name: Anti-ACE (somatic isoform-2) [L10P4F3*F9]
  • Alternate names: ACE antibody ACE T antibody ACE_HUMAN antibody ACE1 antibody Angiotensin converting enzyme somatic isoform antibody Angiotensin converting enzyme testis specific isoform antibody Angiotensin-converting enzyme antibody
  • Clone: L10P4F3*F9
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA ; IHC
  • Strain: Balb/c
  • Description: Ace is an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic forms and the testicular form, respectively, that are equally active. This antibody is specific to ACE-somatic isoform 2 (P12821-2).
  • Immunogen: Ovalbumin-conjugated synthetic peptide QFHPFSQHT (C-terminal sequence)
  • Isotype: IgG
  • Research area: Cancer ; Cell Signaling & Signal Transduction ; Metabolism
  • Myeloma used: P3X63Ag8.653

  • For Research Use Only

Target Details

  • Target: Angiotensin Converting Enzyme, Somatic Isoform-2, (P12821-2)
  • Target background: Ace is an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic forms and the testicular form, respectively, that are equally active. This antibody is specific to ACE-somatic isoform 2 (P12821-2).

Application Details

  • Application: ELISA ; IHC

Handling

  • Format: Liquid
  • Shipping conditions: Shipping at 4°C

Documentation

  • Available on request