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Contributor Information

Tool Details

  • Tool name: Anti-HuD/HuC/Hel-N1 humanized [232]
  • Alternate names: Hu proteins, ELAV-like protein 4
  • Clone: 232
  • Tool type: Antibodies
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human ; Mouse ; Rabbit ; Xenopus laevis ; Zebrafish
  • Host: Human
  • Application: IHC ; IF ; WB
  • Description: Hu proteins are RNA-binding proteins involved in diverse biological processes. The individual members Hel-N1(HuB), HuC, and HuD play important roles in neuronal differentiation and plasticity. The expression of these proteins serves as an excellent neuronal marker. These proteins are typically found in the nucleus , but can be transported to the cytoplasm. The classic monoclonal antibody (16A11) used to identify these proteins only identifies the cytoplasmic fraction. Whereas this recombinant humanized monoclonal recognizes the major nuclear fraction of HuD/HuC and Hel-N1. Thus it has the potential to uncover new biological functions and associations.
  • Immunogen: HuD
  • Isotype: IgG
  • Research area: Developmental biology; Genetics; Neurobiology

  • For Research Use Only

Target Details

  • Target: HuD, HuC, Hel-N1 (HuB)
  • Target background: Hu proteins are RNA-binding proteins involved in diverse biological processes. The individual members Hel-N1(HuB), HuC, and HuD play important roles in neuronal differentiation and plasticity. The expression of these proteins serves as an excellent neuronal marker. These proteins are typically found in the nucleus , but can be transported to the cytoplasm. The classic monoclonal antibody (16A11) used to identify these proteins only identifies the cytoplasmic fraction. Whereas this recombinant humanized monoclonal recognizes the major nuclear fraction of HuD/HuC and Hel-N1. Thus it has the potential to uncover new biological functions and associations.

Application Details

  • Application: IHC ; IF ; WB
  • Application notes: Use anti-human IgG as a secondary antibody

Handling

  • Format: Liquid
  • Storage buffer:
  • Storage conditions:
  • Shipping conditions: Shipping at 4°C

Documentation

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