Anti-eAg Antibody from X63 Fused CD19 B Cell Hybridoma (D4)
- Name Anders Elm Pedersen ; Mogens H Claesson
- Institute University of Copenhagen
Tool name: Anti-eAg Antibody from X63 Fused CD19 B Cell Hybridoma (D4)
Tool type: Antibodies
Description: Regulatory B cells (Bregs) have been shown to play a role in inflammatory bowel disease (IBD) in humans, as B cell depletion in patients with IBD tends to aggravate the disease. Furthermore it has been demonstrated that co-transfer of eAg-exposed B cells improves symptoms of experimental colitis in the T cell transfer model of colitis.
This eAg-specific B cell hybridoma offers a unique tool to investigate the immune response towards eAgâs in experimental colitis, and potentially, in human IBD.
Research area: Other
- For Research Use Only
- • In vitro cloning and regulatory potential of B cell hybridomas secreting entero-antigen specific antibody.