ANTIBODIES
Contributor Information
- Name Richard Meager
- Institute University of Georgia
Tool Details
- Tool name: Anti-Profilin 1 (PRF1) [mAbPRF1a]
- Alternate names: PRF1
- Tool type: Antibodies
- Tool sub-type: Primary Antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Arabidopsis
- Host: Mouse
- Application: IF ; WB
- Description: Profilin is a low-molecular weight, actin monomer-binding protein that regulates the organization of actin cytoskeleton in eukaryotes. Profilin promotes actin assembly at the barbed end of filaments and causes depolymerization of filaments by binding and sequestering G-actin. Profilin also interacts with several other ligands, such as membrane polyphospho-inositides, short proline rich stretches in proteins, and the Arp 2/3 complex.
- Immunogen: Purified plant Profilin 1
- Isotype: IgG2a
- Research area: Cell Structure and Motility
- For Research Use Only
Target Details
- Target: Profilin 1
- Target background: Profilin is a low-molecular weight, actin monomer-binding protein that regulates the organization of actin cytoskeleton in eukaryotes. Profilin promotes actin assembly at the barbed end of filaments and causes depolymerization of filaments by binding and sequestering G-actin. Profilin also interacts with several other ligands, such as membrane polyphospho-inositides, short proline rich stretches in proteins, and the Arp 2/3 complex.
Application Details
- Application: IF ; WB
Handling
- Format: Liquid
- Shipping conditions: Shipping at 4°C
Documentation
- Available on request
Related Tools
References
- • Kandasamy et al. 2002. Cell Motil Cytoskeleton. 52(1):22-32. PMID: 11977080.
- • Plant profilin isovariants are distinctly regulated in vegetative and reproductive tissues.
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