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Contributor Information

  • Institute University of Cambridge

Tool Details

  • Tool name: Anti-Human Insulin receptor (IR) [18-40]
  • Alternate names: IR, hIR, INSR
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Molecular weight of the target: 135 kDa
  • Description: Human Insulin Receptor (IR) is a transmembrane tyrosine kinase receptor for insulin. It plays a role in glucose homeostasis by controlling the glucose transport to cells. Malfunction of IR include clinical manifestations such as cancer and diabetes.
  • Immunogen: Affinity-purified human insulin receptor
  • Isotype: IgG1
  • Research area: Cell Signaling & Signal Transduction; Metabolism
  • Myeloma used: NS0

  • For Research Use Only

Target Details

  • Target: Human Insulin receptor
  • Target molecular weight: 135 kDa
  • Target background: Human Insulin Receptor (IR) is a transmembrane tyrosine kinase receptor for insulin. It plays a role in glucose homeostasis by controlling the glucose transport to cells. Malfunction of IR include clinical manifestations such as cancer and diabetes.

Application Details

Handling

  • Format: Liquid
  • Shipping conditions: Shipping at 4°C

Documentation

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  • Available on request

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References

  • •  Soos et al. 1986. Biochem J. 235(1):199-208. PMID: 2427071.
  • •  Monoclonal antibodies reacting with multiple epitopes on the human insulin receptor.