ANTIBODIES
Contributor Information
- Name Pranab K Das
Tool Details
- Tool name: Anti-Mycobacterial 65-kDa hsp [Nd4]
- Tool type: Antibodies
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Mycobacterium bovis ; Mycobacterium avium
- Host: Mouse
- Application: ELISA ; IHC ; WB
- Strain: Balb/c
- Description: The 65 kDa protein from M.tuberculosis and M.leprae contains a striking degree of sequence homology, differing in only 28 amino acids. This antibody can distinguish the two making it potentially useful in the serodiagnosis of tuberculosis and leprosy. In addition the C-terminal epitope of mycobacterial 65-kDa hsp is shared with human epidermal suprabasal cytokeratin 1/2 making this antibody a marker of cytokeratin 1/2.
- Immunogen: 65-kDa antigen isolated from M.tuberculosis (RIVM-strain 7114)
- Isotype: IgG1
- Research area: Microbiology; Immunology
- Myeloma used: P3X63Ag8.653
- For Research Use Only
Target Details
- Target: Mycobacterial 65-kDa hsp
- Target background: The 65 kDa protein from M.tuberculosis and M.leprae contains a striking degree of sequence homology, differing in only 28 amino acids. This antibody can distinguish the two making it potentially useful in the serodiagnosis of tuberculosis and leprosy. In addition the C-terminal epitope of mycobacterial 65-kDa hsp is shared with human epidermal suprabasal cytokeratin 1/2 making this antibody a marker of cytokeratin 1/2.
Application Details
- Application: ELISA ; IHC ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1mg/ml
- Storage buffer: RPMI 1640
- Storage conditions: -15Ă°C to -25Ă°C
- Shipping conditions: Shipping at 4Ă°C
Documentation
Related Tools
References
- • Rambukkana et al. 1992. Immunology. 77(2):267-76. PMID: 1385316.
- • Rambukkana et al. 1991. FEMS Microbiol Immunol. 3(1):39-45. PMID: 1711877.
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