ANTIBODIES
Contributor Information
- Name Thomas Leung
- Institute A*STAR Accelerate Technologies Pte Ltd
Tool Details
- Tool name: Anti MRCKa [2A3]
- Tool type: Antibodies
- Class: Monoclonal
- Conjugate: Unconjugated
- Application: IP ; WB
- Description: The MRCKLRAP35a-MYO18A complex plays a major role in the assembly of the lamellar actomyosin retrograde flow bundles important for persistent membrane protrusion. The complex may also represent a mode of transmitting signals from leading edge to cell center, as part of the coordination mechanism important for efficient and persistent directional migration.
- Research area: Cell Structure and Motility
- For Research Use Only
Target Details
- Target: MRCKĂ?
- Target background: The MRCKLRAP35a-MYO18A complex plays a major role in the assembly of the lamellar actomyosin retrograde flow bundles important for persistent membrane protrusion. The complex may also represent a mode of transmitting signals from leading edge to cell center, as part of the coordination mechanism important for efficient and persistent directional migration.
Application Details
- Application: IP ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15°C to -25°C
- Shipping conditions: Shipping at 4°C
Documentation
- Available on request
Related Tools
References
- • Tan et al. 2008. Cell. 135(1):123-36. PMID: 18854160.
- • A tripartite complex containing MRCK modulates lamellar actomyosin retrograde flow.
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