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Contributor Information

  • Institute University of Birmingham

Tool Details

  • Tool name: Anti-CD81 [2s48]
  • Alternate names: 26 kDa cell surface protein TAPA-1,Target of the antiproliferative antibody 1, Tetraspanin-28
  • Tool type: Antibodies
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA ; FACS ; IF ; WB
  • Strain: Balb/c
  • Description: CD81 is co-opted during the life cycle of diverse human pathogens: it is involved in hepatitis C virus (HCV) and Plasmodium sporozoite invasion of hepatocytes, and also contributes to the assembly and budding of human immunodeficiency virus and influenza A virus. Developed as a part of panel of murine monoclonal antibodies against full-length CD81 to further examine and assessed their ability to inhibit or neutralize HCV infection.
  • Immunogen: P60033, CD81_HUMAN
  • Immunogen UniProt ID: P60033, CD81_HUMAN
  • Research area: Immunology ; Virology
  • Myeloma used: NS0

  • For Research Use Only

Target Details

  • Target: CD81 and its second extracellular domain (EC2)
  • Target background: CD81 is co-opted during the life cycle of diverse human pathogens: it is involved in hepatitis C virus (HCV) and Plasmodium sporozoite invasion of hepatocytes, and also contributes to the assembly and budding of human immunodeficiency virus and influenza A virus. Developed as a part of panel of murine monoclonal antibodies against full-length CD81 to further examine and assessed their ability to inhibit or neutralize HCV infection.

Application Details

  • Application: ELISA ; FACS ; IF ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

  • Available on request

References

  •   Tkachuk et al. 1975. FEBS Lett. 52(1):66-8. PMID: 1123084.