ANTIBODIES
Contributor Information
- Institute University of Birmingham
Tool Details
- Tool name: Anti-CD81 [2s66]
- Alternate names: 26 kDa cell surface protein TAPA-1,Target of the antiproliferative antibody 1, Tetraspanin-28
- Tool type: Antibodies
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; FACS ; IF ; WB
- Strain: Balb/c
- Description: CD81 is co-opted during the life cycle of diverse human pathogens: it is involved in hepatitis C virus (HCV) and Plasmodium sporozoite invasion of hepatocytes, and also contributes to the assembly and budding of human immunodeficiency virus and influenza A virus. Developed as a part of panel of murine monoclonal antibodies against full-length CD81 to further examine and assessed their ability to inhibit or neutralize HCV infection.
- Immunogen: P60033, CD81_HUMAN
- Immunogen UniProt ID: P60033, CD81_HUMAN
- Research area: Immunology; Virology
- Myeloma used: NS0
- For Research Use Only
Target Details
- Target: CD81 and its second extracellular domain (EC2)
- Target background: CD81 is co-opted during the life cycle of diverse human pathogens: it is involved in hepatitis C virus (HCV) and Plasmodium sporozoite invasion of hepatocytes, and also contributes to the assembly and budding of human immunodeficiency virus and influenza A virus. Developed as a part of panel of murine monoclonal antibodies against full-length CD81 to further examine and assessed their ability to inhibit or neutralize HCV infection.
Application Details
- Application: ELISA ; FACS ; IF ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15°C to -25°C
- Shipping conditions: Shipping at 4°C
Documentation
- Available on request
Related Tools
References
- • Tkachuk et al. 1975. FEBS Lett. 52(1):66-8. PMID: 1123084.
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