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Contributor Information

  • Institute Netherlands Cancer Institute

Tool Details

  • Tool name: Anti-CD23 [5E3]
  • Alternate names: FCER2; Lymphocyte IgE Receptor; Fc-Epsilon-RII
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Molecular weight of the target: 25 kDa
  • Application: FACS
  • Strain: Balb/c
  • Description: CD23 is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. Unlike many of the antibody receptors, CD23 is a C-type lectin. It is found on mature B cells, activated macrophages, eosinophils, follicular dendritic cells, and platelets.
  • Immunogen: Daudi (human Burkitt's lymphoma cell-line)
  • Isotype: IgG1
  • Research area: Cell Signaling & Signal Transduction ; Immunology
  • Myeloma used: Sp2/0-Ag14

  • For Research Use Only

Target Details

  • Target: CD23
  • Target molecular weight: 25 kDa
  • Target background: CD23 is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. Unlike many of the antibody receptors, CD23 is a C-type lectin. It is found on mature B cells, activated macrophages, eosinophils, follicular dendritic cells, and platelets.

Application Details

  • Application: FACS

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

  • Available on request