ANTIBODIES
Contributor Information
- Institute Netherlands Cancer Institute
Tool Details
- Tool name: Anti-CD23 [5E3]
- Alternate names: FCER2; Lymphocyte IgE Receptor; Fc-Epsilon-RII
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Molecular weight of the target: 25 kDa
- Application: FACS
- Strain: Balb/c
- Description: CD23 is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. Unlike many of the antibody receptors, CD23 is a C-type lectin. It is found on mature B cells, activated macrophages, eosinophils, follicular dendritic cells, and platelets.
- Immunogen: Daudi (human Burkitt's lymphoma cell-line)
- Isotype: IgG1
- Research area: Cell Signaling & Signal Transduction ; Immunology
- Myeloma used: Sp2/0-Ag14
- For Research Use Only
Target Details
- Target: CD23
- Target molecular weight: 25 kDa
- Target background: CD23 is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. Unlike many of the antibody receptors, CD23 is a C-type lectin. It is found on mature B cells, activated macrophages, eosinophils, follicular dendritic cells, and platelets.
Application Details
- Application: FACS
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15°C to -25°C
- Shipping conditions: Shipping at 4°C
Documentation
- Available on request
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