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Contributor Information

  • Institute Yale University

Tool Details

  • Tool name: Anti-IA of b,f,p,q,r,s,u,v [Y3JP]
  • Tool type: Antibodies
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Host: Mouse
  • Description: Monoclonal antibody capable of inhibiting I-A-restricted T cell responses. Background and Research Application: The anti-IA monoclonal antibody reacts with mouse MHC Class II haplotypes I-Ab, I-Af, I-Ap, I-Aq, I-Ar, I-As, I-Au, I-Av, and weakly with I-Ak. This antibody is reported to inhibit I-A-restricted T cell responses.
  • Immunogen: P11911
  • Immunogen UniProt ID: P11911
  • Isotype: IgG2a
  • Research area: Immunology

  • For Research Use Only

Target Details

  • Target: IA b,f,p,q,r,s,u,v
  • Target background: Monoclonal antibody capable of inhibiting I-A-restricted T cell responses. Background and Research Application The anti-IA monoclonal antibody reacts with mouse MHC Class II haplotypes I-Ab, I-Af, I-Ap, I-Aq, I-Ar, I-As, I-Au, I-Av, and weakly with I-Ak. This antibody is reported to inhibit I-A-restricted T cell responses.

Application Details

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Campisi et al. 2016. Nat Immunol. 17(9):1084-92. PMID: 27455420.
  • •  Feng et al. 2015. Nature. 528(7580):132-136. PMID: 26605529.
  • •  Guo et al. 2015. Nat Immunol. 16(10):1051-9. PMID: 26322482.
  • •  Janeway CA et al. 1984. J Immunol. 132(2):662-7. PMID: 6228596.