ANTIBODIES
Contributor Information
- Institute Yale University
Tool Details
- Tool name: Anti-heat stable antigen [20C9]
- Tool type: Antibodies
- Tool sub-type: Primary Antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Description: Monoclonal antibody with a broad spectrum of inhibitory effects on the expansion of T cells induced via TCR. Background and Research Application Signal transducer CD24 also known as cluster of differentiation 24 or heat stable antigen CD24 (HSA) is a cell adhesion molecule encoded by the CD24 gene. Anti-HSA significantly inhibits the proliferation of CD4 T cells induced by anti-CD3 or by allogeneic LPS-activated B cells. Engagement of the TCR in the presence of this monoclonal antibody leads to functional inactivation of T cells.
- Immunogen: P07900
- Immunogen UniProt ID: P07900
- Research area: Immunology
- For Research Use Only
Target Details
- Target: Heat Stable Antigen
- Target background: Monoclonal antibody with a broad spectrum of inhibitory effects on the expansion of T cells induced via TCR. Background and Research Application Signal transducer CD24 also known as cluster of differentiation 24 or heat stable antigen CD24 (HSA) is a cell adhesion molecule encoded by the CD24 gene. Anti-HSA significantly inhibits the proliferation of CD4 T cells induced by anti-CD3 or by allogeneic LPS-activated B cells. Engagement of the TCR in the presence of this monoclonal antibody leads to Fn inactivation of T cells.
Application Details
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: Store at -20°C frozen. Avoid repeated freeze / thaw cycles
- Shipping conditions: Shipping at 4°C
Documentation
- Available on request
References
- • Li et al. 2006. J Exp Med. 203(7):1713-20. PMID: 16769998.
- • Bai et al. 2004. J Exp Med. 200(4):447-58. PMID: 15314074.
- • Liu et al. 1992. J Exp Med. 175(2):437-45. PMID: 1346270.
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