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Contributor Information

  • Name Xiang-ming Zha
  • Institute University of South Alabama

Tool Details

  • Tool name: Anti-ASIC2 [ASIC2]
  • Tool type: Antibodies
  • Tool sub-type: Primary Antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Mouse
  • Host: Rabbit
  • Application: IHC ; WB
  • Description: Acid-sensing ion channels (ASICs) are proton-gated ion channels expressed predominantly in neurons. In the brain, the main ASIC subunits are ASIC1a, ASIC2a and ASIC2b. ASICs have been shown to regulate synaptic function, fear, learning, and are one important contributor to pain and neuronal injuries.
  • Immunogen: Raised using the following peptides: PGDAPYCTPE, CFDYIYELIKEKLLD, CETISHTVNVPLQTA, SHTVNVPLQTALGTLEEIAC (SHT), and VPLQTALGTLEEIAC (VPL)
  • Research area: Neurobiology

  • For Research Use Only

Target Details

  • Target: Acid-sensing ion channel (ASIC) 2
  • Target background: Acid-sensing ion channels (ASICs) are proton-gated ion channels expressed predominantly in neurons. In the brain, the main ASIC subunits are ASIC1a, ASIC2a and ASIC2b. ASICs have been shown to regulate synaptic function, fear, learning, and are one important contributor to pain and neuronal injuries.

Application Details

  • Application: IHC ; WB

Handling

  • Format: Liquid
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Wu et al. 2016. Mol Brain. 9:4. PMID: 26746198.