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Contributor Information

  • Institute Medical Research Council; University of Oxford

Tool Details

  • Tool name: Anti-CD172a [OX41]
  • Tool type: Antibodies
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Rat
  • Host: Mouse
  • Application: FACS ; IHC ; WB
  • Description: The antibody recognises a rat macrophage cell surface antigen and labels all peritoneal and 90% of alveolar macrophages. Splenic red pulp macrophages are antigen +ve, marginal zone macrophages antigen -ve. The antibody also reacts with the 120kDa antigen on granulocytes and dendritic cells and recognises rat SIRP (personal communication).
  • Immunogen: Resident peritoneal cells from (PVG-RT1c x PVG RT1u)F1 and (PVG-RT1c x DA-RT1a)F1 rats
  • Myeloma used: NS0/U

  • For Research Use Only

Target Details

  • Target: CD172a (signal regulatory protein, SIRP)
  • Target background: The antibody recognises a rat macrophage cell surface antigen and labels all peritoneal and 90% of alveolar macrophages. Splenic red pulp macrophages are antigen +ve, marginal zone macrophages antigen -ve. The antibody also reacts with the 120kDa antigen on granulocytes and dendritic cells and recognises rat SIRP (personal communication).

Application Details

  • Application: FACS ; IHC ; WB

Handling

  • Format: Liquid
  • Storage buffer:
  • Storage conditions:
  • Shipping conditions: Shipping at 4°C

Documentation

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  • Available on request

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References

  • •  Robinson et al. 1986. Immunology. 57(2):239-47. PMID: 3512425.