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Contributor Information

  • Institute University of Georgia

Tool Details

  • Tool name: Anti-Alpha-TgCenH3 (TgCenpA) [CenpA]
  • Alternate names: T. gondii centromeric histone 3 variant (CenH3)
  • Tool type: Antibodies
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Arabidopsis
  • Application: IF
  • Description: The phylum Apicomplexa includes various parasites that cause several human diseases including malaria and toxoplasmosis. These parasites are able to invade human hosts through a complex budding process. The budding process of Toxoplasma gondii was recently shown to require the centrocone. The centromeric histone 3 variant (CenH3) is part of this centrocone and can be visualized using the TgCenpA antibody.
  • Research area: Microbiology; Cell biology

  • For Research Use Only

Target Details

  • Target: T. gondii centromeric histone 3 variant (CenH3)
  • Target background: The phylum Apicomplexa includes various parasites that cause several human diseases including malaria and toxoplasmosis. These parasites are able to invade human hosts through a complex budding process. The budding process of Toxoplasma gondii was recently shown to require the centrocone. The centromeric histone 3 variant (CenH3) is part of this centrocone and can be visualized using the TgCenpA antibody.

Application Details

  • Application: IF

Handling

  • Format: Liquid
  • Storage buffer:
  • Storage conditions:
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Alvarez et al. 2017. PLoS Pathog. 13(7):e1006483. PMID: 28671988.
  • •  Brooks et al. 2011. Proc Natl Acad Sci U S A. 108(9):3767-72. PMID: 21321216.