- Name Urpo LamminmÄÂ¤ki
- Institute University of Turku
Tool name: Anti-GTP [2A4]
Tool type: Antibodies
Tool sub-type: Primary antibody
Application: ELISA ; FACS ; IF
Description: GTPases are central cellular signaling proteins, which cycle between a GDP-bound inactive and a GTP-bound active conformation in a controlled manner. Ras GTPases are frequently mutated in cancer and so far only few experimental inhibitors exist. The most common methods for monitoring GTP hydrolysis rely on luminescent GDP- or GTP-analogs. (From Kopra et al Anal. Chem. 2015, 87, 6, 3527ÄËĂÂĂÂ3534)
Research area: Cancer; Metabolism
- For Research Use Only
- • Kopra et al. 2017. Anal Chem. 89(8):4508-4516. PMID: 28318223.
- • Kopra et al. 2015. Anal Chem. 87(6):3527-34. PMID: 25707436.