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Contributor Information

  • Name Abdo Alnabulsi
  • Institute Vertebrate Antibodies Limited

Tool Details

  • Tool name: Anti-CRP/SAP-1a [A13 P1B11*G7]
  • Tool type: Antibodies
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Salmonids
  • Host: Mouse
  • Molecular weight of the target: 26
  • Application: ELISA ; IHC ; WB
  • Strain: Balb/c
  • Description: The classical pentraxins, C-reactive protein (CRP) and serum amyloid P component (SAP) are serum opsonins, which bind to damaged membranes and nuclear autoantigens. Pentraxins are important in the process of complement activation and clearance of apoptotic bodies through FcÎ? receptors. Pentraxins are well conserved in arthropods, fish, amphibians, and mammals. In salmon, CRP/SAP-1a is reported as one of the major acute phase proteins (APPs) and were significantly up-regulated by recombinant cytokines (rIL-1Î? and rIFN-Î?) in primary head kidney cells. This is the only commercial antibody available.
  • Immunogen: Ovalbumin-conjugated synthetic peptide. Peptide immunogen is conserved in salmonids fish species.
  • Isotype: IgG1 kappa
  • Research area: Cell Type or Organelle Marker; Immunology

  • For Research Use Only

Target Details

  • Target: Pentraxin precursor
  • Target molecular weight: 26
  • Target background: The classical pentraxins, C-reactive protein (CRP) and serum amyloid P component (SAP) are serum opsonins, which bind to damaged membranes and nuclear autoantigens. Pentraxins are important in the process of complement activation and clearance of apoptotic bodies through FcÎ? receptors. Pentraxins are well conserved in arthropods, fish, amphibians, and mammals. In salmon, CRP/SAP-1a is reported as one of the major acute phase proteins (APPs) and were significantly up-regulated by recombinant cytokines (rIL-1Î? and rIFN-Î?) in primary head kidney cells. This is the only commercial antibody available.

Application Details

  • Application: ELISA ; IHC ; WB

Handling

  • Format: Liquid
  • Storage buffer:
  • Storage conditions:
  • Shipping conditions: Shipping at 4°C

Documentation

  • Available on request