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Contributor Information

  • Institute Moravian Biotechnology

Tool Details

  • Tool name: Anti-STUB1 [CHIP-11.1]
  • Alternate names: E3 ubiquitin-protein ligase CHIP
  • Tool type: Antibodies
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human ; Mouse
  • Host: Mouse
  • Application: WB
  • Description: E3 ubiquitin-protein ligase which targets misfolded chaperone substrates towards proteasomal degradation. Collaborates with ATXN3 in the degradation of misfolded chaperone substrates: ATXN3 restricting the length of ubiquitin chain attached to STUB1/CHIP substrates and preventing further chain extension
  • Immunogen: Q9UNE7
  • Immunogen UniProt ID: Q9UNE7
  • Research area: Cancer

  • For Research Use Only

Target Details

  • Target: CHIP
  • Target background: E3 ubiquitin-protein ligase which targets misfolded chaperone substrates towards proteasomal degradation. Collaborates with ATXN3 in the degradation of misfolded chaperone substrates: ATXN3 restricting the length of ubiquitin chain attached to STUB1/CHIP substrates and preventing further chain extension

Application Details

  • Application: WB

Handling

  • Format: Liquid
  • Shipping conditions: Shipping at 4°C

Documentation

  • Available on request