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Contributor Information

  • Name Prof Martin Clynes
  • Institute Dublin City University
  • Primary citation O’Sullivan D, et al. 2014. Tumor Biol. 6983-97. PMID: 24744142

Tool Details

  • Tool name: Anti-Ku70/Ku80 [7B7]
  • Clone: 7B7
  • Tool type: Antibodies
  • Tool sub-type: Primary Antibody
  • Class: Monoclonal
  • Conjugate: No
  • Reactivity: Human
  • Host: Mouse
  • Cancer type: Pancreatic cancer; Lung cancer
  • Disease: Cancer
  • Application: WB, IP, IHC, ELISA
  • Description: 7B7 clone targets the Ku70/Ku80 heterodimer and can significantly reduce invasion in a dose-responsive manner in MiaPaCa-2 clone3 and DLKP-M squamous lung carcinoma cells.
  • Isotype: IgM
  • Research area: Cancer

  • For Research Use Only

Target Details

  • Target: Ku70/Ku80 heterodimer 
  • Target background: heterodimeric Ku antigen, Ku70/80, a core protein composed of the Ku70 and Ku80 subunits which is involved in non-homologous end-joining (NHEJ) DNA repair.

Application Details

  • Application: WB, IP, IHC, ELISA

Handling

  • Storage buffer: PBS with 0.02% azide
  • Storage conditions:  -15°C to -25°C
  • Shipping conditions: 4°C

Documentation

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References

  • •  O’Sullivan D, et al. 2014. Tumor Biol. 6983-97. PMID: 24744142