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Contributor Information

  • Name Allan Balmain
  • Institute Cancer Research UK, Glasgow: The Beatson Institute

Tool Details

  • Tool name: PDVC57B Cell Line
  • Tool type: Cell Lines
  • Tool sub-type: Continuous
  • Parental cell line: PDV
  • Organism: Mouse
  • Cancer type: Carcinoma
  • Disease: Cancer
  • Growth properties: Mouse spindle cell carcinoma, Adherent
  • Model: Tumour line
  • Description: The PDVC57B Cell Line is useful for the study of the progression of carcinogenesis and as a model of relapse after surgery. PDVC57B is syngeneic for C57B1/6 mice and carries a p53 mutation in codon 231, (ATG-GTC) and an A-T tranversion at cod 61 of the H-ras gene. These events appear to be remarkably similar to the sequence of changes seen during tumour development in vivo.
  • Research area: Cancer; Apoptosis and autophagy; Cell biology; Drug development; Genetics
  • Production details: The transformed PDVB57B was created by treating the PDV cell line with the carcinogen DMBA.
  • Cellosaurus ID: CVCL_4271

  • For Research Use Only

Target Details

  • Target: PDVC57b

Application Details


  • Format: Frozen
  • Growth medium: DMEM + 2mM Glutamine + 10% Foetal Bovine Serum (FBS).
  • Shipping conditions: Dry ice



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  •   Comparison of ras activation during epidermal carcinogenesis in vitro and in vivo.