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Contributor Information

  • Name Sharon Tooze
  • Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details

  • Tool name: MEF ULK1 ULK2 DKO (SIM) Cell Line
  • Tool type: Cell Lines
  • Parental cell line:
  • Organism: Mouse
  • Tissue: Embryo
  • Disease: Cancer, neurodegeneration, infectious disease
  • Conditional: Yes
  • Description: The MEF ULK1 ULK2 DKO (SIM) cell line provides a tool for the study of Ulk1 and Ulk2 and of Autophagy. Mouse embryonic fibroblast Ulk1/Ulk2 double knock-out cell line is from an embryo with a mixed genetic background (Blk6/129 Agouti).
  • Research area: Cancer ; Apoptosis and Programmed Cell Death ; Cell Signaling & Signal Transduction ; Metabolism ; Neurobiology

  • For Research Use Only

Target Details

Application Details


  • Format: Frozen
  • Growth medium: DMEM + 20% FCS + 2mM Glutamine + pen/strep
  • Storage conditions: Liquid Nitrogen
  • Shipping conditions: Dry ice
  • Mycoplasma free: Yes
  • Biosafety level: 1


  • Available on request


  •   McAlpine et al. 2013. Autophagy. 9(3):361-73. PMID: 23291478.
  •   Regulation of nutrient-sensitive autophagy by uncoordinated 51-like kinases 1 and 2.