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Contributor Information

  • Name Sharon Tooze
  • Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details

  • Tool name: MEF ULK2 KO (SIM) Cell Line
  • Tool type: Cell Lines
  • Parental cell line:
  • Organism: Mouse
  • Tissue: Embryo
  • Disease: Cancer, neurodegeneration, infectious disease
  • Description: The MEF ULK2 KO (SIM) cell line provides a tool for the study of Ulk2 and of Autophagy and has a comparable genetic background to MEF Ulk1 Ulk2 DKO and MEF Ulk1 KO cell lines. Mouse embryonic fibroblast Ulk2 knock-out cell line is derived from an embryo with a mixed genetic background (Blk6/129B Agouti) similar to MEF Ulk1 Ulk2 DKO cell line.
  • Research area: Cancer ; Apoptosis and Programmed Cell Death ; Cell Signaling & Signal Transduction ; Metabolism ; Neurobiology

  • For Research Use Only

Target Details

Application Details


  • Format: Frozen
  • Growth medium: DMEM + 20% FCS + 2mM Glutamine + pen/strep
  • Shipping conditions: Dry ice


  • Available on request


  •   McAlpine et al. 2013. Autophagy. 9(3):361-73. PMID: 23291478.
  •   Regulation of nutrient-sensitive autophagy by uncoordinated 51-like kinases 1 and 2.