CELL LINES

Contributor Information
- Name Jennifer Nichols
- Institute University of Oxford
Tool Details
- Tool name: LF2 Cell Line
- Tool type: Cell Lines
- Organism: Mouse
- Tissue: Embryo
- Conditional: No
- Description: The LF2 mouse embryonic stem cell line is a germ-line competent embryonic stem cell line that inactivates one of its X chromosomes upon retinoic acid treatment. Embryonic stem cells provide a powerful system for the experimental analysis of mammalian development. Their genetic manipulation allows the introduction of defined modifications into the mouse germ-line, whilst in culture they constitute both an assay system for, and a potential source of, embryonic regulatory factors.
- Research area: Genetics; Stem cell biology
- Cellosaurus ID: CVCL_AS05
- For Research Use Only
Related Tools
References
- • Evans et al. Development 110, 1341-1348 (1990).