SVCT-MI2 Cell Line
- Name Joyce Taylor-Papadimitriou ; Sidney Chang
- Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool name: SVCT-MI2 Cell Line
Tool type: Cell Lines
Parental cell line:
Cancer type: Breast Cancer
Description: SVCT-MI2 was established in 1987 from epithelial cells in breast milk secretions. The cells have been transfected by microinjection using SV40 DNA and a plasmid containing the neomycin gene and the human oncogene EJ Harvey-ras. After selection of G418-resistant colonies, the clone SVCT-MI2 was shown to be tumorigenic in nude mice. They also have the ability to grow anchorage-independent if cultured in soft agar.
Research area: Cancer ; Cell Cycle ; Drug Discovery & Development ; Epigenetics & Nuclear Signalling
- For Research Use Only
- • Yamashita et al. 2009. Bioorg Med Chem. 17(17):6286-91. PMID: 19674905.
- • Synthesis and evaluation of bioactive naphthoquinones from the Brazilian medicinal plant, Tabebuia avellanedae.