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Contributor Information

  • Name Sidney Chang
  • Institute Marie Curie Research Institute

Tool Details

  • Tool name: SVCT Cell Line
  • Tool type: Cell Lines
  • Organism: Human
  • Tissue: Breast
  • Cancer type: Breast Cancer
  • Disease: Cancer
  • Growth properties: Adherent
  • Model: Immortalised Line
  • Conditional: Yes
  • Description: SVCT has been established from human breast epithelial cells being transfected with SV40. The cell line shows an abnormal karyotype and was not tumourigenic in athymic male nude mice. SVCT have been found positive for the expression of keratin 7, 8 and 18 but negative for keratin 19. Epithelial cells, dome formation when confluent.
  • Research area: Cancer ; Drug Discovery & Development
  • Cellosaurus ID: CVCL_2718

  • For Research Use Only

Target Details

Application Details

Handling

  • Format: Frozen
  • Growth medium: DMEM + 2mM Glutamine + 5Äžg/ml Hydrocortisone + 10Äžg/ml Insulin + 10% Foetal Bovine Serum (FBS).
  • Shipping conditions: Dry ice

Documentation

  • Available on request

References

  •   Chang et al. 1986. Biochim Biophys Acta. 823(3):161-94. PMID: 2423124.
  •   In vitro transformation of human epithelial cells.