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Contributor Information

  • Name Sidney Chang
  • Institute Marie Curie Research Institute
  • Primary citation Chang et al. 1986. Biochim Biophys Acta. 823(3):161-194. PMID: 2423124.

Tool Details

  • Tool name: SVCT Cell Line
  • Tool type: Cell Lines
  • Organism: Human
  • Tissue: Breast
  • Gender: Female
  • Cancer type: Breast cancer
  • Disease: Cancer
  • Growth properties: Adherent
  • Model: Immortalised Line
  • Conditional: Yes
  • Description: SVCT has been established from human breast epithelial cells being transfected with simian virus 40 (SV40) - a known oncogenic DNA virus. This cell line has a dome formation when confluent.

    This transformed epithelial cell line shows an abnormal karyotype and was not tumourigenic in athymic male nude mice.

    SVCT has been found to be positive for the expression of keratin 7, 8 and 18 but negative for keratin 19.
  • Research area: Cancer; Drug development
  • Cellosaurus ID: CVCL_2718

  • For Research Use Only

Target Details

Application Details

Handling

  • Format: Frozen
  • Growth medium: DMEM + 2mM Glutamine + 5ug/ml Hydrocortisone + 10ug/ml Insulin + 10% Foetal Bovine Serum (FBS).
  • Temperature: 37° C
  • Atmosphere: 5% CO2
  • Shipping conditions: Dry ice

Documentation

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References

  • •  Chang et al. 1986. Biochim Biophys Acta. 823(3):161-194. PMID: 2423124.