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Contributor Information

  • Name Eric Kenneth Parkinson
  • Institute Cancer Research UK Glasgow: The Beatson Institute

Tool Details

  • Tool name: BICR 22 Cell Line
  • Tool type: Cell Lines
  • Organism: Human
  • Tissue: Tongue
  • Cancer type: Tongue squamous carcinoma (lymph node metastasis)
  • Disease: Cancer
  • Growth properties: Adherent
  • Model: Tumour line
  • Conditional: Yes
  • Description: Adherent cell line derived from a lymph node metastasis squamous cell carcinoma of the tongue of a Caucasian male. Keratin and involucrin markers present. Known mutations: p53, p16 and p14ARF. Cells are tumourigenic in athymic mice.
  • Research area: Cancer ; Apoptosis and Programmed Cell Death ; Drug Discovery & Development ; Epigenetics & Nuclear Signalling
  • Cellosaurus ID: CVCL_2310
  • Additional notes: Amelogenin: X, X CSF1PO: 11 D13S317: 11,13 D16S539: 11,12 D5S818: 11,12 D7S820: 11,12 THO1: 6,7 TPOX: 8 vWA: 16,19

  • For Research Use Only

Target Details

Application Details

  • Application notes: Amelogenin: X, X CSF1PO: 11 D13S317: 11,13 D16S539: 11,12 D5S818: 11,12 D7S820: 11,12 THO1: 6,7 TPOX: 8 vWA: 16,19

Handling

  • Format: Frozen
  • Growth medium: DMEM + 2mM Glutamine + 10% Foetal Bovine Serum (FBS) + 0.4 micrograms/ml Hydrocortisone.
  • Shipping conditions: Dry ice

Documentation

  • Available on request

References

  •   Edington et al. 1995. Mol Carcinog. 13(4):254-65. PMID: 7646764.
  •   Cellular immortality: a late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss.